Personalized vaccine for recurrent glioma
Part of Cancer clinical trials.
This trial tests a personalized vaccine created by AI to target your specific brain tumor. It is for people with a glioma that came back after standard treatments like surgery, radiation, or chemotherapy, and whose tumor has enough genetic mutations to make the vaccine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a glioma (a type of brain tumor) that came back after standard treatments like surgery, radiation, or chemotherapy.
- Your tumor must have many genetic changes (high mutation load) and at least 10 new targets (neoantigens) for the vaccine to recognize.
- You must be able to give a sample of your tumor and blood for testing.
- You need to have at least one tumor that can be seen on an MRI scan.
- You should be in fairly good health (able to care for yourself and with good blood, liver, and kidney function).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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