Lung infusion for colorectal cancer that has spread to the lungs
Treatments studied
Part of Bones, joints & muscles, Cancer, Digestive system clinical trials.
This trial tests a procedure where chemotherapy is delivered directly into the lungs during surgery to remove or destroy lung tumors. It aims to reduce the chance of cancer returning after surgery for people with colorectal cancer that has spread to the lungs.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have colorectal cancer that has spread to your lungs and the lung tumors can be removed or destroyed with surgery or other methods.
- You are generally able to care for yourself (ECOG performance status of 2 or less).
- Your blood counts and kidney function are within acceptable levels.
- Your lungs are healthy enough for surgery, as determined by your surgeon.
- You have not had chemotherapy or radiation in the last 4 weeks (or 6 weeks for certain drugs).
- You do not have brain metastases, severe nerve damage, or allergies to chemotherapy drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 trial tests a targeted treatment delivered to the lungs for colorectal cancer that has spread to the lungs. It aims to see if the approach is safe and can reach lung tumors, especially when there are multiple lung lesions.
This trial tests a combination of three chemotherapy drugs (liposomal irinotecan, oxaliplatin, and capecitabine) given directly into the liver blood vessel after surgery to remove colorectal cancer that has spread to the liver. The goal is to reduce the chance of cancer coming back.
This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.
This trial tests giving chemotherapy directly into the liver artery after surgery to remove liver tumors. It's for people with colorectal cancer that spread to the liver, who have a high chance of the cancer coming back.
This trial studies giving targeted high-dose radiation (SBRT) to liver metastases from colorectal cancer after initial treatment, with the goal of improving long-term control or cure. It may help people who have a limited number of liver spots that doctors think can be treated safely and effectively.
This early-phase study tests a special way to deliver medicine directly to the lungs (called IVLP) for sarcoma that has spread to both lungs. It aims to control lung metastases while reducing side effects, and it uses a plan that often includes surgery or focused radiation around the procedure.
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