Clin2
NCT07284394Possibly a fitNot yet recruiting

Liver chemotherapy after surgery for colorectal cancer spread

Colorectal Adenocarcinoma Metastatic in the LiverColorectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial tests whether giving chemotherapy directly into the liver after surgery can lower the chance of cancer coming back. It is for people who had multiple liver tumors removed and whose cancer did not grow during pre-surgery chemo.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
272 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older
  • You have had surgery to remove 4 or more liver tumors from colorectal cancer
  • You had chemo before surgery and your tumors shrank or stayed the same
  • You are healthy enough to get chemo into your liver through a small tube
  • You do not have cancer growing elsewhere, except up to 3 small lung spots
  • You agree to use birth control if needed

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07570914Not yet recruiting· Phase 2
Adjuvant liver infusion after colorectal cancer liver surgery

This trial tests a treatment given directly into the liver after surgery to remove colorectal cancer that has spread to the liver. The goal is to see if this treatment lowers the chance of the cancer coming back.

NCT03494946Recruiting
Liver transplant vs chemotherapy for colon cancer liver spread

This trial compares liver transplantation to standard chemotherapy for people with colon or rectal cancer that has spread to the liver but cannot be removed surgically. It looks at whether transplant can help patients live longer or better than chemotherapy in the right patients.

Oslo
NCT06501482Recruiting· Phase 3
Chemotherapy after liver surgery for colorectal cancer that spread to the liver

This trial tests giving patients a type of chemotherapy called FOLFIRI after they have had surgery to remove colorectal cancer that spread to the liver. The goal is to see if this additional treatment helps prevent the cancer from coming back, for patients who could not have a different chemotherapy before surgery.

Paris, Île-de-France Region
NCT05815082Recruiting· Phase 3
ctDNA-guided chemo after liver surgery for colon cancer

This trial checks whether giving chemotherapy after surgery only for people whose blood test (ctDNA) shows no remaining cancer can help prevent the cancer from coming back. It is for people with colon cancer that has spread to the liver who had the tumor fully removed.

Guangzhou, Guangdong
NCT06280495Recruiting· Phase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread

This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.

Guangzhou, Guangdong
NCT01479608Recruiting
Liver transplant for colon or rectal cancer liver spread

This trial studies whether a liver transplant can help people with colon or rectal cancer that has spread to the liver (but not elsewhere). It aims to improve outcomes by removing the diseased liver when the cancer has responded to chemotherapy and can still be controlled.

Oslo

Hear when a new Colorectal Adenocarcinoma Metastatic in the Liver trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.