Clin2
NCT07284394Possibly a fitNot yet recruiting

Chemotherapy into liver artery after liver surgery for colorectal cancer

Colorectal Adenocarcinoma Metastatic in the LiverColorectal Cancer

Part of Cancer, Digestive system clinical trials.

This trial tests giving chemotherapy directly into the liver artery after surgery to remove liver tumors. It's for people with colorectal cancer that spread to the liver, who have a high chance of the cancer coming back.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
272 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have stage IV colorectal cancer that has spread to the liver
  • You had surgery to remove at least 4 tumors from your liver
  • Your tumors responded to chemotherapy before surgery (stable or shrunk)
  • You are willing to receive chemotherapy directly into the artery that supplies your liver
  • You have no major nerve damage or liver problems that would prevent this treatment

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07570914Not yet recruiting· Phase 2
Chemotherapy after surgery for colorectal cancer with liver spread

This trial tests a combination of three chemotherapy drugs (liposomal irinotecan, oxaliplatin, and capecitabine) given directly into the liver blood vessel after surgery to remove colorectal cancer that has spread to the liver. The goal is to reduce the chance of cancer coming back.

NCT07764497Recruiting· Phase 2
Chemotherapy through liver artery for colorectal cancer that spread to liver

This trial tests giving chemotherapy directly into the liver artery for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to shrink the tumors and make the liver healthy enough for surgery.

Toronto, Ontario
NCT05815082Recruiting· Phase 3
ctDNA-guided chemo after liver surgery for colon cancer

This trial checks whether giving chemotherapy after surgery only for people whose blood test (ctDNA) shows no remaining cancer can help prevent the cancer from coming back. It is for people with colon cancer that has spread to the liver who had the tumor fully removed.

Guangzhou, Guangdong
NCT06280495Recruiting· Phase 2/Phase 3
Targeted drugs plus chemo before surgery for colon cancer with liver spread

This trial tests whether adding two targeted drugs (serplulimab and bevacizumab) to standard chemotherapy before surgery can improve outcomes for people with colorectal cancer that has spread to the liver. It is for those whose cancer has certain genetic features and is considered resectable.

Guangzhou, Guangdong
NCT03494946Recruiting
Liver transplant vs chemotherapy for colon cancer liver spread

This trial compares liver transplantation to standard chemotherapy for people with colon or rectal cancer that has spread to the liver but cannot be removed surgically. It looks at whether transplant can help patients live longer or better than chemotherapy in the right patients.

Oslo
NCT06988852Recruiting· Phase 2
Chemo infusion into liver for colorectal cancer spread

This trial tests a strong chemotherapy combination given directly into the liver's blood supply (called HAIC) for people whose colorectal cancer has spread only to the liver and cannot be removed with surgery yet. The goal is to shrink the liver tumors enough so they can be surgically removed.

Wuhan, Hubei

Hear when a new Colorectal Adenocarcinoma Metastatic in the Liver trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.