Clin2
NCT04003506Possibly a fitNot yet recruiting

Nerve block with long-acting pain medicine for knee replacement

Pain, Postoperative

Treatments studied

Part of Pain clinical trials.

This study looks at a type of pain relief called a nerve block (adductor canal block) using a long-lasting medicine (liposomal bupivacaine) after knee replacement surgery. It aims to see if this approach reduces pain and helps you recover better after surgery.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
90 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old
  • You are scheduled for your first total knee replacement on one knee only
  • You can speak and understand Cantonese
  • You are in generally good health (American Society of Anesthesiologists class I-III)
  • You do not have severe heart disease, kidney problems, or a history of chronic pain (other than knee pain)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06740214Recruiting· Phase 3
Different doses of liposomal bupivacaine for knee replacement pain

This trial tests different doses of a long-acting painkiller (liposomal bupivacaine) injected into a nerve block in the thigh to see which dose works best for pain after knee replacement surgery. It may help you have better pain control and recover faster.

Hong Kong, Hong Kong
NCT07855341Not yet recruiting· Phase 4
Nerve block study for hip replacement pain relief

This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.

Cairo, Cairo Governorate
NCT06653621Not yet recruiting· Phase 4
Comparing two nerve blocks for knee replacement pain

This study tests two types of pain relief injections after total knee replacement to see which provides better pain control with fewer side effects. It compares a long-lasting liposome bupivacaine to standard bupivacaine, given in two different nerve block locations.

Wuhan, Hubei
NCT07616102Not yet recruiting
Long-lasting numbing medicine for knee replacement recovery

This study tests a long-lasting numbing medicine (liposomal bupivacaine) given during knee replacement surgery. The goal is to see if it helps preserve muscle strength after surgery while still controlling pain.

Yinchuan, Ningxia
NCT07629388Recruiting
Nerve block for pain after knee replacement surgery

This trial tests whether adding a nerve block (a numbing injection near the nerve) to the usual pain plan can better control pain after a total knee replacement. The goal is to help you recover with less pain and fewer side effects.

Dijon
NCT07191964Not yet recruiting
Nerve block for pain after knee replacement

This trial tests a nerve block that helps manage pain after total knee replacement surgery. It may reduce the need for strong painkillers and improve your recovery. The study is for people having their first knee replacement on one knee.

Taipei

Hear when a new Pain, Postoperative trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.