Clin2
NCT06653621Possibly a fitNot yet recruiting

Comparing two nerve blocks for knee replacement pain

Knee ArthropathyKnee Arthritis

Treatments studied

Part of Bones, joints & muscles, Pain clinical trials.

This study tests two types of pain relief injections after total knee replacement to see which provides better pain control with fewer side effects. It compares a long-lasting liposome bupivacaine to standard bupivacaine, given in two different nerve block locations.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
144 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 80 years old
  • You are having a total knee replacement on one knee (not both at once)
  • You are in generally good health (classified as ASA I to III)
  • You do not have diabetes-related nerve damage
  • You have not been taking strong painkillers (opioids) for a long time
  • Your body mass index (BMI) is under 35

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06864663Not yet recruiting
Comparing two pain relief methods for knee replacement surgery

This study compares two different pain-block methods used during total knee replacement surgery to see which gives better pain relief. The goal is to help patients have less pain and a better recovery after surgery.

Cairo
NCT04808947Not yet recruiting
Comparing two pain relief methods for knee replacement surgery

This study compares two ways to manage pain after knee replacement surgery: one uses a local anesthetic injection around the knee, and the other adds an additional nerve block. The goal is to see which method provides better pain relief and recovery.

NCT04003506Not yet recruiting· Phase 4
Nerve block with long-acting pain medicine for knee replacement

This study looks at a type of pain relief called a nerve block (adductor canal block) using a long-lasting medicine (liposomal bupivacaine) after knee replacement surgery. It aims to see if this approach reduces pain and helps you recover better after surgery.

Hong Kong
NCT07876310Not yet recruiting
Comparing two numbing shots for pain after knee replacement

This trial compares two different nerve blocks to see which one controls pain better after knee replacement surgery. Both are given along with a continuous pain pump, and the goal is to improve recovery with fewer side effects.

NCT07739108Not yet recruiting
Nerve block comparison for pain after knee replacement

This study compares two types of nerve blocks to see which provides better pain relief after knee replacement surgery. Participants will receive one of the two blocks and use a patient-controlled pain pump, and the study will track their pain levels and recovery.

NCT07130552Recruiting
Comparing two pain relief methods after knee replacement

This study tests two different nerve-block techniques to see which provides better pain control after total knee replacement surgery. The goal is to help you recover more comfortably.

Karaman

Hear when a new Knee Arthropathy trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.