Testing common blood-pressure drugs on uterine and umbilical muscle
Treatments studied
Part of Heart & circulation, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests how several medicines used for blood pressure affect muscle “tightening” in tissue taken during planned C-sections. It’s an in-vitro (lab) study, so it mainly helps doctors understand how to prevent weak uterine contractions (uterine atony) during delivery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You can sign a written consent form to join the study
- You are between 19 and 40 years old
- You are between 37 and 41 weeks pregnant
- Your C-section is planned (elective primary or first repeat), and you are not in labor
- You will have spinal anesthesia (not general anesthesia) and you’re not receiving oxytocin to start labor
- You are not taking medicines that can change uterine muscle strength (examples: insulin, nifedipine, labetolol, magnesium sulfate)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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