Treatment
Phenylephrine clinical trials
We’re tracking 24 recruiting studies that include Phenylephrine, each written for real people, not researchers, below.
Recruiting studies
- NCT07420127RecruitingPhase 4
Comparing two doses of a blood pressure drug during c-section
This trial tests two different doses of phenylephrine, a medicine used to manage blood pressure, in women having a planned cesarean section. It aims to see how each dose affects a common drug given to help the uterus contract after birth.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07033845RecruitingEarly Phase 1
Absorption Study of Topical Phenylephrine in Healthy Women
This study tests how a topical phenylephrine solution is absorbed through the scalp in healthy women. It aims to understand the drug's safety and how the body processes it.
RomeAges 18–55 - NCT06836986Recruiting
Norepinephrine vs. phenylephrine for blood pressure in C-section
This trial compares two medications, norepinephrine and phenylephrine, to see which works better at preventing low blood pressure during emergency C-sections under spinal anesthesia.
Karachi, SindhAges 18–40 - NCT04053478Recruiting
Testing common blood-pressure drugs on uterine and umbilical muscle
This study tests how several medicines used for blood pressure affect muscle “tightening” in tissue taken during planned C-sections. It’s an in-vitro (lab) study, so it mainly helps doctors understand how to prevent weak uterine contractions (uterine atony) during delivery.
Toronto, OntarioAges 19–40 - NCT06248593RecruitingPhase 4
Continuous Norepinephrine vs Phenylephrine for Cesarean Blood Pressure
This study compares two medicines (norepinephrine and phenylephrine) given continuously through a vein to keep your blood pressure stable during a planned cesarean with spinal anesthesia. It aims to see which medicine works better for you and your baby.
FesAges 18–45 - NCT06334549RecruitingPhase 4
Vasopressor study on brain oxygen during surgery
This study tests how a blood-pressure medicine called a vasopressor affects oxygen levels in the brain during general anesthesia for abdominal surgery. It may help patients understand the safest way to manage blood pressure during their operation.
Dalian, LiaoningAges 18–80 - NCT06539637RecruitingEarly Phase 1
Ketorolac levels in eye fluid during cataract and vitrectomy surgery
This study looks at how much of the drug ketorolac (a pain and inflammation medicine) gets into the fluid inside your eye when it's given as eye drops during combined cataract and vitrectomy surgery. It may help doctors understand if using another drug called phenylephrine alongside it changes those levels.
Westbury, New YorkAges 18 years+ - NCT01731444RecruitingPhase 1
Phenylephrine gel to reduce bleeding in burn skin surgery
This early-stage study tests a medication (phenylephrine) used during burn wound surgery to help control bleeding. If it works, it may make skin grafting safer and reduce how much bleeding surgeons see.
Winnipeg, ManitobaAges 18–75 - NCT02323399RecruitingPhase 4
IV medicine study for blood pressure effects during anesthesia
This trial studies how phenylephrine given through an IV affects blood pressure during procedures under general or spinal/epidural anesthesia. It may help doctors understand how to control blood pressure more safely during surgery.
Wilmington, DelawareAges 12–16 - NCT04934748Enrolling by invitationPhase 4
Blood pressure medication study during major non-heart surgery
This trial tests how doctors manage blood pressure during major surgery using common medicines (norepinephrine or phenylephrine). It may help by improving safety for people at higher risk of blood pressure drops or complications during surgery.
Omaha, NebraskaAges 45 years+ - NCT07662408RecruitingPhase 4
Comparing two drugs to prevent low blood pressure during hip surgery
This trial tests two different medicines (norepinephrine and phenylephrine) given as an infusion to prevent low blood pressure after spinal anesthesia for hip surgery. It may help older adults undergoing planned hip replacement or repair.
SohagAges 60–100 - NCT04500899RecruitingPhase 1/Phase 2
Phenylephrine test to better grade mitral valve leak severity
This trial tests whether a medication called phenylephrine helps doctors measure how severe mitral regurgitation (mitral valve leak) is. If you’re already scheduled for a special ultrasound from the esophagus, this study may help improve how your valve leak is assessed.
New York, New YorkAges 18 years+ - NCT05997732RecruitingPhase 4
Blood Pressure Control: Sex Differences in Healthy Adults
This study looks at how the nervous system controls blood pressure differently in men and women. It involves a single visit where you'll receive a small dose of medications through an IV and have your nerve activity and blood pressure measured.
Edmonton, AlbertaAges 18–40 - NCT06083948RecruitingPhase 2/Phase 3
Blood pressure medicines and brain blood flow during tumor surgery
This study tests how different blood pressure medicines affect blood flow to the brain and other organs during anesthesia for brain tumor surgery. It aims to find the safest way to keep your brain healthy while you are asleep.
AarhusAges 18–75 - NCT06285396Recruiting
Diabetes and medication effects on uterine muscle during C-section
This trial studies how three medications (ephedrine, phenylepinephrine, and norepinephrine) affect the contraction strength of uterine muscle tissue from pregnant people with type 2 or gestational diabetes during planned C-sections. It aims to understand if these drugs act differently in people with diabetes, which could help tailor safer treatments for low blood pressure during surgery.
Toronto, OntarioAges 19–45 - NCT06499467Recruiting
Comparing second blood pressure medicines for septic shock
This trial tests different combinations of blood pressure medicines given to patients on a breathing machine who have septic shock. The goal is to find the best dose of a second medicine when norepinephrine alone isn't enough.
Lucknow, Uttar PradeshAges 18–80 - NCT06677970RecruitingPhase 3
Blood Pressure Control After Stroke Thrombectomy
This trial tests whether carefully lowering blood pressure after a mechanical clot removal procedure for stroke can improve outcomes. If you've had a large vessel stroke that was successfully treated with thrombectomy, this study will help guide blood pressure management in the recovery period.
Seoul, SeoulAges 20 years+ - NCT06711432Recruiting
Blood Pressure Management During Tumor Surgery and Brain Function
This trial compares different blood pressure management strategies during abdominal tumor surgery to see which one better protects cognitive function (thinking, memory, and clarity). It is for patients who have multiple stroke risk factors and are undergoing a lengthy surgery.
Hangzhou, ZhejiangAges 40–85 - NCT06802224RecruitingPhase 4
Medication to prevent kidney injury after major surgery
This study compares two medications given during surgery to see which one better protects the kidneys after the procedure. If you are having major non-cardiac surgery that lasts at least 2 hours and you need medication to support your blood pressure, this trial may be a good fit.
San Francisco, CaliforniaAges 18 years+ - NCT07178600Recruiting
Eye drops for surgery: side effects study
This study looks at how patients react to a common eye drop used before surgery. It helps understand side effects and who might be affected.
Mexico City, Mexico CiyAges 18 years+ - NCT02118467RecruitingPhase 4
Testing medicines that raise blood pressure in ICU shock patients
This trial studies whether “blood pressure–supporting” medicines (given through a central line) work well and safely for adults in the ICU who have shock. Your team may use the results to improve care for people with low blood pressure and poor blood flow to organs.
Chicago, IllinoisAges 18 years+ - NCT02560805RecruitingPhase 2
Study drugs that affect stress nerves and blood pressure in PTSD
This Phase 2 study looks at how stress-related nerve activity and a hormone called angiotensin II may be involved in PTSD, and how specific blood-pressure-related medicines affect the body. You may be eligible if you are a PTSD patient (or a matched control without PTSD) and meet safety criteria.
Decatur, GeorgiaAges 18–65 - NCT02673996Recruiting
Study of POTS body chemical signals and blood pressure control
This trial studies people with POTS (a condition where heart rate rises when you stand) and compares them with people without POTS. It tests body “adrenergic” (stress-chemistry) signals and how the body handles posture, which may help researchers find better ways to manage POTS.
Calgary, AlbertaAges 18–60 - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50
What Phenylephrine is being studied for
Conditions with recruiting Phenylephrine studies.
Common questions
- Are there clinical trials studying Phenylephrine?
- Yes. Clin2 currently lists 24 recruiting studies that include Phenylephrine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Phenylephrine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Phenylephrine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Phenylephrine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.