Avoid extra lymph-node radiation for certain node-positive breast cancers
Part of Cancer, Skin clinical trials.
This trial tests a way to decide whether you can safely receive less radiation to lymph nodes after surgery for breast cancer that has spread to nearby nodes. If you qualify as “low risk,” the goal is to reduce radiation exposure while keeping cancer control safe.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 to 70 years old, and generally able to do most daily activities (ECOG 0–2).
- Your surgery pathology confirms invasive breast cancer and specific types of lymph-node involvement (small “micrometastasis” or limited node spread).
- You had breast-conserving surgery or a full breast removal with reconstruction (not just total mastectomy with only a sentinel node biopsy).
- You completed at least 4 rounds of standard chemotherapy after surgery (or may skip chemo only for some hormone-receptor/low-risk test results).
- There’s no sign of spread to distant organs on scans done within 3 months before radiation, and no other breast cancer on the opposite side in the prior 12 months.
- Your medical records must allow the lab test called “RecurIndex,” using your stored tumor tissue.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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