Radiation without lymph node biopsy for low-risk early breast cancer
Part of Cancer, Skin clinical trials.
This trial is testing whether radiation therapy to just the breast (not the lymph nodes) is safe and effective for women with early-stage, low-risk breast cancer. It aims to see if omitting the sentinel node biopsy is acceptable when the cancer has not spread to the lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 40 or older.
- You have invasive breast cancer that has not spread to the lymph nodes and is 2 cm or smaller (about the size of a pea).
- Your cancer is only in one spot in the breast, with no other areas of cancer in the same breast or the other breast.
- You had breast-conserving surgery (lumpectomy) to remove the cancer, and the edges around the removed tissue were free of cancer.
- The cancer has a low or intermediate aggressiveness (grade 1 or 2) and did not show invasion into blood or lymph vessels.
- You did not have sentinel lymph node biopsy during surgery, and you have not had radiation to the chest or breast before.
- You do not have a known BRCA gene mutation, and you have not had breast cancer before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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