Radiation to lymph nodes after surgery for higher-risk breast cancer
Part of Cancer, Skin clinical trials.
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and were assigned female at birth
- You had breast cancer surgery (either breast-conserving surgery or mastectomy) plus sentinel or armpit lymph node surgery, and your lymph nodes were negative for cancer
- Your cancer is invasive and staged as T1 to T3, with no nodes and no distant spread (T1-3N0M0, Stage IA–IIB)
- Your pathology shows at least two “high-risk” features: tumor size over 2 cm, tumor in the inner/central breast area, Ki-67 over 14%, and/or tumor blood vessel spread is positive
- You have recovered from surgery enough for radiation (incisions healed, no infection) and your health status is good enough for treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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