Brain scan study to predict fluoxetine response in OCD
Part of Mental health clinical trials.
This study looks at how brain networks change before and after starting fluoxetine (an SSRI antidepressant) in people with obsessive-compulsive disorder (OCD). It also compares these brain scan patterns with people without OCD to help predict who may respond to treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are an adult and able to complete all study visits and brain scans
- If you have OCD: you have a confirmed OCD diagnosis and your symptoms are at least moderately severe (Y-BOCS 16+)
- If you have OCD: you are not currently taking “mood/psychiatric” medications (except occasional sleep medicine when needed)
- You can safely have an MRI scan (no metal in your body and you can lie still for a long scan)
- You are not pregnant and will use reliable birth control if you could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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