Idebenone to prevent episodic migraine attacks
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests idebenone, a preventive medicine, to see if it can reduce how often migraine attacks happen. It mainly focuses on people with episodic migraine who have regular attacks and are not already using other migraine prevention treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a clinical diagnosis of episodic migraine (not chronic migraine).
- You are age 18 to 65 and meet headache-migraine criteria based on the International Headache Society.
- You have 2 to 8 migraine attacks per month, and you don’t have constant, day-after-day headaches.
- You are not overusing “as-needed” migraine pain medicines.
- You are not taking migraine preventive medicine, and if you were, it’s been at least 3 months since stopping.
- You have not taken idebenone recently (within 14 days) and have never had to stop idebenone due to side effects.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests new ways to monitor how well preventive migraine treatments are working. It is for people with chronic migraine who may be starting or already using preventive medications.
This trial compares two medicines taken daily to prevent migraine headaches, with the goal of reducing how often they happen.
This study tests an investigational medication called NB001 for treating migraine attacks as they happen. If you have frequent migraines, this treatment might help reduce the severity or shorten the duration of your attacks.
This trial tests a new medicine, MEDI0618, against a placebo for people with episodic migraine. The goal is to see if MEDI0618 is safe and effective at reducing migraine days.
This trial tests whether a daily dose of atorvastatin (a common cholesterol medicine) can prevent migraine attacks in people with episodic migraine. You would keep a headache diary and be randomly assigned to take atorvastatin or a placebo for about 3 months.
This trial tests whether a medication called rimegepant can prevent migraines when you take it before a known trigger (like exercise or stress). It is for people who get migraines often and can predict when one might happen.
Hear when a new Migraine Disorders trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.