FDOPA PET scan to locate excess insulin in infancy
Part of Digestive system, Genetic & congenital, Hormones & metabolism clinical trials.
This Phase 2 study uses an FDOPA PET scan to find where insulin overproduction is coming from in focal congenital hyperinsulinism (FoHI) or related conditions. The goal is to help doctors better detect and localize the “source” so treatment can be more targeted.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of focal or related congenital hyperinsulinism (FoHI/DiHI) based on blood sugar and insulin pattern testing
- Genetic testing has found a disease-causing change in ABCC8 or KCNJ1
- Low blood sugar (hypoglycemia) is not well controlled with standard medicines like diazoxide or octreotide
- You can stop certain medicines in time for the PET scan (you have a clear “washout” plan)
- Your liver and kidneys are working normally
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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