Test of strong chemotherapy delivered inside the abdomen
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This Phase 2 trial tests an intensive treatment for advanced ovarian, fallopian tube, or primary peritoneal cancer. It combines planned surgery to remove visible tumor with chemotherapy that is put directly inside the abdomen during the operation, aiming to control the cancer more effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 75 years old
- Your cancer is high-grade serous ovarian, fallopian tube, or primary peritoneal cancer (confirmed by biopsy/pathology)
- You had a diagnostic laparoscopy that shows how widespread it is and confirms it could not be fully removed at first
- Your cancer stage is usually IIIb/IIIc, or stage IVA with only a small-to-moderate fluid buildup around the lungs (pleural effusion less than 3 cm on CT)
- You can have complete “interval debulking” surgery after 3 to 4 cycles of chemo, with surgery 4 to 8 weeks after the last chemo cycle
- Your blood tests and organs function well enough for treatment (blood counts, liver, and kidneys), and you can safely receive intensive surgery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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