Cryoablation plus pembrolizumab and chemotherapy for lung cancer spread
Treatments studied
Part of Cancer clinical trials.
This trial studies whether freezing a small number of lung cancer spots (cryoablation) alongside standard immunotherapy (pembrolizumab) and chemotherapy can improve outcomes in people with metastatic lung adenocarcinoma. It’s meant for people who have measurable tumors that can be safely targeted with the freezing treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed lung adenocarcinoma (not squamous) based on lab tests on tissue or cells.
- Your cancer has spread to other parts of the body (metastatic disease).
- You will be receiving pembrolizumab with pemetrexed-carboplatin as the study treatment plan.
- You have at least two measurable tumor spots on CT or MRI, including one that can be treated with cryoablation (freezing).
- You are 18 or older, and your overall functioning is not too limited (performance status 0–2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests combining a drug called serplulimab with a freezing treatment (cryoablation) for people with early-stage non-small cell lung cancer. The goal is to see if using both treatments together helps more than freezing alone.
This trial tests whether adding an immunotherapy drug (serplulimab) to a procedure called cryoablation (freezing tumors) works better than cryoablation alone for people with early-stage non-small cell lung cancer that has not spread. It is for patients who cannot or choose not to have surgery or radiation.
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