Cryoablation with immunotherapy for multiple lung cancers
Part of Cancer, Lungs & breathing clinical trials.
This trial tests freezing tumors (cryoablation) combined with two drugs (Karelizumab and Apatinib) for people who have several small lung cancer spots in their lungs but no spread to lymph nodes. The goal is to see if this combination is safe and helps shrink or control the tumors.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have multiple lung cancers that started in the lungs (not spread from elsewhere), with at least 3 spots initially, and no cancer in lymph nodes.
- The largest tumor spot must be 3 cm or smaller (about 1.2 inches).
- If you've had surgery before, you must have at least 2 remaining spots, and the removed ones were very early-stage (MIA or AIS).
- You must be between 18 and 75 years old and feeling well enough for daily activities (ECOG score 0 or 1).
- Your blood counts, liver, and kidney function must be within certain limits (your doctor can check this).
- You cannot have certain gene changes (EGFR, ALK) or have had certain immunotherapy drugs before.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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