Testing depression treatment options for people with advanced kidney disease
Treatments studied
Part of Kidney & urinary, Mental health, Women’s health & pregnancy clinical trials.
This Phase 2 study tests a combination of new depression treatments for adults living with advanced chronic kidney disease (CKD) and major depression. It may help by improving depression symptoms, while also checking that the treatments are safe for people with reduced kidney function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 or older (no upper age limit).
- You have advanced CKD (stages 3b, 4, or 5) for at least 3 months, with kidney function below 45.
- You currently have major depression diagnosed by a structured screening interview.
- Your depression scores must be high enough at both screening and enrollment check-ins.
- You can understand and sign the study consent form.
- If you’ve had a kidney transplant, you must be at least 6 months after transplant (with confirmatory kidney function checks).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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