Medication boost for tough-to-treat chronic depression
Part of Mental health clinical trials.
This trial tests a new medication added to your current treatment for chronic depression that hasn't gotten better with at least two antidepressants and 12 therapy sessions. It might help when standard treatments aren't enough.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 64 years old.
- You have been diagnosed with chronic depression—either recurrent episodes without full recovery, or a single episode lasting two years or more.
- You have tried at least two different antidepressants from two different medication classes, and they didn't work well enough.
- You have completed at least 12 sessions of therapy (like cognitive behavioral therapy) for your depression.
- You are not currently struggling with substance misuse as a primary problem, and you have no serious medical conditions like uncontrolled high blood pressure, epilepsy, or recent heart problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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