Clin2
NCT04482660Possibly a fitEnrolling by invitation

PET brain scan study of tau protein in ALFA volunteers

HealthyMild Cognitive Impairment

Part of Mental health clinical trials.

This study uses a special PET brain scan tracer to measure “tau” protein clumps in the brain. It’s meant to better understand brain changes in people who are already part of the ALFA research program, and may help researchers connect tau levels with memory and thinking.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
100 people
Ages
45 years and older
Study type
Interventional

Who can take part

  • You can sign the study consent form
  • You have taken part in past Barcelonabeta (BBRC) ALFA-related studies
  • You have a brain MRI from the last 12 months with no concerning incidental findings
  • Your recent study results include your current thinking/cognition status and whether you have “AB” and tau changes
  • You can read and speak the study language well enough to follow instructions
  • If you are female: you are post-menopausal, or your pregnancy test is negative at the time of the PET scan

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05582200Recruiting
PET brain scan to study inflammation cells in Alzheimer’s

This study uses a special PET brain scan to look at two types of brain immune cells in people with Alzheimer’s. It may help researchers better understand Alzheimer’s and how these cells change over time.

Houston, Texas
NCT03372317Recruiting
Tau brain PET imaging study for adults ages 55–90

This study uses a brain scan called PET to look at tau (a brain protein) and how it relates to thinking and memory. It may help researchers understand early brain changes, though it’s mainly for healthy people living near Columbia who have had an amyloid PET scan before.

New York, New York
NCT07169630Recruiting· Phase 1
PET scan study for Alzheimer's or mild cognitive impairment

This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.

Bethesda, Maryland
NCT02685969Recruiting
Brain scan study of amyloid and brain sugar use

This study uses brain imaging to measure two things in the brain—amyloid protein and how the brain uses sugar. It may help researchers better understand early brain changes in people in the ALFA project.

Barcelona, Catalonia
NCT07752784Recruiting· Phase 3
Tau brain imaging in people with mild thinking changes or Alzheimer's

This study uses a special PET scan to take pictures of abnormal tau protein in the brain. It aims to see if the scan results match what is found in brain tissue after death, which could help improve diagnosis of Alzheimer's and related conditions.

Beijing, Beijing Municipality
NCT02414347Recruiting
Tau PET scan study for Alzheimer’s disease

This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.

St Louis, Missouri

Hear when a new Mild Cognitive Impairment trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.