Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT06058234Recruiting
Tracking Alzheimer’s treatment for Medicare patients in early stages
This study tracks how well a certain type of Alzheimer’s treatment works for people on Medicare who are in the early stages of the disease. The goal is to collect real-world information about the drug’s benefits and risks.
Baltimore, MarylandAges Any age - NCT03020381Recruiting
Study of walking patterns to predict dementia and falls
This study looks at how your walking (gait) might help predict future dementia and risk of falls. You may be asked to walk tests and have health information collected to see who is at higher risk.
London, OntarioAges 60–85 - NCT06705738Recruiting
Mediterranean diet and olive compound for mild memory loss
This study tests whether a Mediterranean diet combined with a natural compound found in extra virgin olive oil (oleocanthal) can help people with mild memory problems (mild cognitive impairment). It aims to see if this combination can slow down or improve memory decline.
Thessaloniki, ThessalonikiAges 60–85 - NCT07866768Recruiting
Ultrasound treatment to clear brain waste in early memory loss
This study tests a low-intensity ultrasound treatment aimed at helping the brain clear out harmful protein buildup linked to Alzheimer's disease. It is for people 65 and older with mild cognitive impairment (slight but noticeable memory problems) and a positive test for amyloid, a protein in the brain.
San Francisco, CaliforniaAges 65 years+ - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+ - NCT06005038RecruitingPhase 1
Memory training study for older adults with mild cognitive issues
This study tests a computer-based memory training program to see if it can improve memory and thinking skills in older adults with mild cognitive impairment. It may help you if you have memory concerns but still live independently.
Palo Alto, CaliforniaAges 60 years+ - NCT07835399Recruiting
Light therapy for mild cognitive impairment and mild Alzheimer's disease
This trial tests if shining a special light through the scalp and nose can help people with mild memory or thinking problems. It aims to slow down memory decline and improve daily life.
BeijingAges 50–85 - NCT06467253Recruiting
Brain stimulation plus memory training for mild memory loss
This study tests two gentle brain stimulation methods combined with memory training for people with mild memory loss. It aims to help improve thinking and memory skills over 8 weeks at a psychiatric hospital in Mexico City.
Mexico CityAges 55–85 - NCT07818369Recruiting
Gut bacteria and fiber supplement for mild memory problems
This study tests whether a daily supplement containing special bacteria and fiber from agave (a type of prebiotic) can improve memory and thinking in older adults with mild cognitive impairment. It looks at the connection between the gut and the brain.
Mexico City, Mexico CityAges 60–75 - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+ - NCT07803055Recruiting
Blood test for early signs of Alzheimer's disease
This study looks at tiny particles in the blood that may show early signs of Alzheimer's disease. It aims to help with earlier diagnosis and monitoring, which could lead to better care and treatment opportunities.
RomeAges 55–80 - NCT07794956RecruitingEarly Phase 1
Memory study for older adults with a care partner
This study tests a dietary product, called LpD3.5, to see if it can help older adults with mild memory problems. You and a care partner would take part together.
Tampa, FloridaAges 60 years+ - NCT07799584Recruiting
Brain stimulation with tai chi for mild memory problems
This study tests a new type of non-invasive brain stimulation combined with tai chi to see if it can improve memory and thinking in older adults with mild cognitive impairment (MCI), a stage between normal aging and dementia. It may help slow down memory decline and improve daily function.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT05534607Recruiting
Community hula program for dementia risk in older Native Hawaiians
This study tests whether joining a community hula (dance) program can help people reduce future dementia risk. It focuses on older Native Hawaiian or Pacific Islander adults who already have mild memory concerns and certain health conditions like high blood pressure or diabetes.
Honolulu, HawaiiAges 50–75 - NCT07786116Recruiting
Gut bacteria in Parkinson's disease and related conditions
This study looks at how certain gut bacteria (methanogens) are involved in the progression of Parkinson's disease and related conditions. It aims to understand the connection between gut health and brain health, which may lead to better treatments.
Cambridge, CB2Ages 55 years+ - NCT07784946Recruiting
A sleep intervention for people with mild cognitive impairment
This study tests a behavioral sleep intervention for people with mild cognitive impairment or mild dementia. It aims to improve sleep and overall well-being. You may qualify if you have mild cognitive impairment and sleep problems.
Kowloon, Hung HomAges 18 years+ - NCT06561906Recruiting
Early Alzheimer's detection using scans, genetics and blood
This study uses brain scans, blood tests, and genetic information to find early signs of Alzheimer's disease before memory problems start. It aims to predict who might develop Alzheimer's in the future.
Nanjing, JiangsuAges 50–79 - NCT07771036Recruiting
Brain stimulation for memory and balance in older adults with mild memory lapses
This study tests a new, non-invasive brain stimulation method (called temporal interference stimulation) to see if it can improve memory and balance while walking in older adults who have mild cognitive impairment. If you qualify, you might receive this stimulation and take part in memory and balance tests.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT07775079Recruiting
Comparing exercise training approaches for older adults with mild memory problems
This study tests two different ways of combining physical and mental exercises to see which helps older adults with mild to moderate memory problems improve their thinking and daily function better.
Islamabad, IslamabadAges 4.6 years–7.1 years - NCT07764250Recruiting
Comparing two balance training approaches for older adults with mild to moderate memory or thinking problems
This study compares two types of balance training (one where you stand still and one where you stand while doing a task) for older adults with mild to moderate thinking or memory problems. It aims to see which training is better for improving balance and daily function.
Islamabad, CapitalAges 55 years+ - NCT06453746Recruiting
Non-drug program to prevent dementia for mild cognitive impairment
This study tests whether non-drug activities (like exercise, brain games, or lifestyle changes) can help prevent dementia in older adults with mild memory loss. You will take part in a program at the hospital and have regular checkups.
Ho Chi Minh CityAges 60 years+
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Mild Cognitive Impairment trials by city
Studies with a site in or near these metro areas.
Mild Cognitive Impairment trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 408 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.