Test for treatment of recurrent rectal cancer in side lymph nodes
Part of Cancer, Digestive system clinical trials.
This trial focuses on rectal cancer that has come back in the side lymph nodes near the pelvis. It tests how to treat that “lateral nodal recurrence” to improve outcomes by targeting these specific lymph nodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- Your rectal cancer has come back in the side lymph nodes (lateral nodes) with suspicious features on scan
- The side lymph node(s) are big enough: at least 7 mm in short-axis, or at least 5 mm with concerning warning signs
- You have not had prior pelvic radiation treatment
- You have not had prior surgery removing side pelvic lymph nodes for a related pelvic cancer
- You do not have distant metastases (cancer spread to organs far away) at the same time, and you are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at how much the lymph nodes respond to chemoradiation before surgery in people with locally advanced rectal cancer. It aims to understand if that response can predict long-term results and guide future treatment choices.
This trial compares two ways of removing lymph nodes (small glands that help fight infection) during robotic surgery for mid or low rectal cancer. It aims to see whether removing fewer lymph nodes may be just as effective and cause fewer side effects than removing a larger group of them.
This study looks at where colorectal cancer spreads to lymph nodes after surgery. It aims to improve how doctors check lymph nodes to better understand the cancer and guide future treatment.
This trial tests a combination of short-course radiation, chemotherapy (capecitabine), and two immunotherapy drugs (PD-1 and CTLA-4 inhibitors) for people with early-stage rectal cancer who want to avoid surgery and keep their anus. The goal is to see if this treatment can shrink the tumor enough to avoid major surgery.
This trial tests giving a higher dose of radiation to people whose rectal cancer has come back in the pelvis after surgery and cannot be removed. It aims to see if more radiation can help control the tumor when surgery is not an option.
This study looks at how doctors decide to treat enlarged lymph nodes in the pelvis for rectal cancer. It aims to help guide whether surgery should remove those lymph nodes, using MRI findings to improve outcomes.
Hear when a new Rectal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.