Colchicine for kidney-related heart inflammation
Treatments studied
Part of Kidney & urinary, Women’s health & pregnancy clinical trials.
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 21 to 80
- Have kidney function in a specific range (eGFR 15 to 75)
- Have higher-than-normal urine protein (albumin-to-creatinine ratio over 30)
- Take appropriate blood pressure/protein-protecting kidney medicines (ACE inhibitor or ARB) unless your clinician says not to
- If indicated, take an SGLT2 inhibitor (a kidney/heart medicine like empagliflozin or dapagliflozin)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether colchicine, a drug that reduces inflammation, can help prevent further heart problems or strokes in people with moderate chronic kidney disease. You may be eligible if you have kidney disease and have had a heart attack, stroke, or related event in the past.
This trial tests if the anti-inflammatory drug colchicine can help people hospitalized with acute heart failure and a weak heart pump. It may benefit those with elevated inflammation markers.
This trial tests if colchicine, an anti-inflammatory medicine, can help people with a type of heart failure where the heart pumps well but is stiff and inflamed. You may join if your heart failure recently worsened and you have signs of inflammation in your blood.
This trial tests if a low dose of colchicine, a medicine that reduces inflammation, can help improve blood vessel and bone health in people with moderate chronic kidney disease.
This trial is testing whether colchicine, a medication used for gout, can help people with a specific type of heart failure where the heart pumps normally but is stiff. If you have heart failure with preserved pumping and certain signs of inflammation, this study might be a good fit.
This study tests if colchicine, a medicine used for gout and inflammation, can help people with coronary heart disease who have had a stent placed. You might be eligible if you have ongoing inflammation (measured by a simple blood test) and are already on standard heart medications.
Hear when a new Chronic Kidney Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.