Low-dose colchicine for heart failure with inflammation
Part of Heart & circulation clinical trials.
This trial tests whether a low-dose colchicine (LoDoCo) can help people with heart failure and inflammation feel better and exercise more. It is for adults 50 and older with HFpEF who have signs of inflammation in their blood.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 50 years old or older.
- You have been diagnosed with heart failure with preserved ejection fraction (HFpEF) in the last 6 months.
- You have a blood test showing a high-sensitivity C-reactive protein (hs-CRP) level of 2 mg/L or higher, which is a sign of inflammation.
- You are able to walk on a treadmill or ride a stationary bike for a heart stress test.
- Your heart medications have been stable for at least 1 month.
- You do not have severe kidney disease (eGFR less than 30) or liver problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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