Clin2
NCT05175274Possibly a fitNot yet recruiting

Colchicine to prevent first heart problems in at-risk adults

Coronary Artery Disease

Treatments studied

Part of Heart & circulation clinical trials.

This study tests whether taking a daily low dose of colchicine, a medicine used for inflammation, can help prevent a first heart attack or other heart problems in people who are at higher risk due to their risk factors. If you qualify, you would be assigned to take either colchicine or a placebo (a pill with no active medicine) to see if it helps keep your heart healthy.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
6,792 people
Ages
40 years to 70 years
Study type
Interventional

Who can take part

  • You must be between 40 and 70 years old.
  • You need to have at least three risk factors for heart disease, such as high blood pressure, high cholesterol, diabetes, smoking, or a family history.
  • You must not already have been diagnosed with coronary artery disease.
  • Your kidneys must be working well (checked by a lab test).
  • You cannot have a history of stroke, heart failure, or other serious heart conditions.
  • You cannot currently be taking colchicine or be allergic to it.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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