Metformin to slow abdominal aortic aneurysm growth
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether metformin, a common diabetes medicine, can slow the growth of an abdominal aortic aneurysm (a bulging area in the main artery in your belly). If you have a small aneurysm, this medicine might help keep it from getting bigger and reduce your risk of needing surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 95 years old.
- You have an abdominal aortic aneurysm that is small to medium in size (about 3.5 to 5 cm for men, 3 to 4.5 cm for women).
- You do not have diabetes and your blood sugar test (HbA1c) is 6.5% or lower.
- Your kidneys work well enough (eGFR of 30 or higher).
- You are willing to take a pill every day and have two CT scans of your belly (one at the start and one at the end of the study).
- You are not pregnant, planning to become pregnant, or breastfeeding (if you are a woman who could have children).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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