Study of genes in people with bicuspid aortic valve
Part of Heart & circulation clinical trials.
This study looks for genetic (inherited) differences that may be linked to bicuspid aortic valve (BAV). It includes people with BAV and close family members to help understand why BAV happens and whether genes play a role.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosed bicuspid aortic valve (BAV) and are age 10 or older
- You can include first-degree relatives (parent, sibling, or child) who are also age 10 or older
- You are able and willing to give informed consent (or have a legal guardian if needed)
- You (and/or your family member) are not known to have HIV, hepatitis B, or hepatitis C
- You do not have known chromosomal/karyotype problems (major chromosome number/structure changes)
- You do not have a known or suspected inherited connective-tissue syndrome such as Marfan, Loeys-Dietz, or Ehlers-Danlos
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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