Denosumab for healing an acute Charcot foot in diabetes
Treatments studied
Part of Hormones & metabolism clinical trials.
This Phase 3 trial tests whether denosumab can improve healing and outcomes for people with an acute Charcot foot caused by diabetes-related nerve problems. You may be able to join if your Charcot foot is recently diagnosed and you meet specific safety and lab requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re between 18 and 80 years old.
- You have type 1 or type 2 diabetes diagnosed for more than 3 months.
- You have an acute Charcot foot in one foot only, with clear signs like redness, swelling, warmth, and confirmed Charcot changes on scans.
- The Charcot episode must be 3 months or less at the screening visit.
- You must not have a foot ulcer or a foot infection in the affected foot.
- You must not have recent denosumab treatment, low calcium or vitamin D, significant kidney problems, or a history of jaw bone problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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