Brexpiprazole for bipolar depression that won’t improve
Treatments studied
Part of Mental health clinical trials.
This Phase 3 study tests whether brexpiprazole can help treat bipolar depression that has not responded to previous treatments. It compares the study medicine to a placebo (inactive pill) for people with bipolar I or II depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 to 75, and you can legally sign consent
- You have bipolar disorder (type I or II) with a current depressive episode
- Your depression has lasted at least 2 weeks but no more than 52 weeks at the start of the study
- You tried at least one other treatment for this current depressive episode and it did not work
- You are taking a mood-stabilizing medicine (for example lithium, valproate, lamotrigine, or low-dose quetiapine)
- Basic health checks are normal at screening (blood tests and heart tracing/EKG)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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