Study drug for bipolar depression in people already on mood stabilizers
Part of Mental health clinical trials.
This trial tests whether OSU6162 can improve depressive symptoms in adults with bipolar depression who are already taking a stable mood-stabilizing medicine. It also checks safety by closely monitoring mood, heart rhythm, and other health factors during the study.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be able to sign consent and be willing to join the psychiatric ward before or right after screening
- Be 18–65 years old at the screening visit
- Have bipolar I or bipolar II disorder with a current depressive episode (confirmed by an interview)
- Have moderate-to-severe depression on a standard depression scale score (Bech 6-item Hamilton depression score ≥10)
- Have been on a stable mood stabilizer dose for at least 4 weeks before screening
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a stronger, more active medication plan for six weeks helps people with bipolar depression who did not improve with their first prescribed treatment. It compares the intensified medication plan to usual care to see which approach works better.
This Phase 3 study tests whether brexpiprazole can help treat bipolar depression that has not responded to previous treatments. It compares the study medicine to a placebo (inactive pill) for people with bipolar I or II depression.
This trial tests whether adding the study drug OSU6162 to your current antidepressant can help when standard medications haven't worked well enough. It aims to reduce depression symptoms over several weeks.
This trial tests an investigational drug called LB-102 for people with bipolar I disorder who are currently experiencing a major depressive episode without psychosis. It aims to see if the drug is safe and effective for treating depression symptoms.
This study is following and assessing people with major depression or bipolar disorder to better understand the condition and how the brain relates to symptoms. It may help researchers develop more targeted support by comparing brain and health information over time.
This study is looking at people with mood disorders like depression or bipolar disorder to better understand their experiences. By joining, you can help researchers learn more about these conditions, which may lead to better care in the future.
Hear when a new Bipolar Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.