Biomarker study to help detect Alzheimer’s early
Part of Brain & nervous system, Mental health clinical trials.
This study looks for brain/biological “signals” (biomarkers) that may identify Alzheimer’s disease earlier, including stages before clear symptoms. You may be followed for about 5 years, with repeated memory and thinking testing to see how these signs relate to future diagnosis.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your legal guardian) must give written consent before any study steps.
- You must be age 18 or older.
- You likely need to have a diagnosis such as early Alzheimer’s, mild cognitive impairment, pre–mild cognitive impairment, or normal thinking with specific markers (like amyloid positive or APOE ε4) based on the study’s criteria.
- You may be asked to complete cognitive testing (for example, memory/thinking questionnaires and scores) and provide biological samples (biospecimens).
- You must have a study “informant” available (someone who can provide information for you) and be able to complete the study visits at the start and during follow-up.
- You must not have certain conditions that could interfere with testing (for example, major brain/neurologic or psychiatric illnesses that can cause dementia) and you cannot have refused the cognitive test or specimen collection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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