Safety study of EP0042 for certain AML patients
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This Phase 1/2 study tests how safe and tolerable EP0042 is, and looks at patients with a specific type of AML that has come back or did not respond to prior treatment. You may be considered if your AML diagnosis is confirmed and your lab tests, overall health, and medication history fit the study rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re age 18 or older and have AML confirmed by lab tests (look at blood/cell samples under a microscope).
- You can sign consent in writing and understand the study steps, including allowing use of stored (archival) tissue if available.
- You can take and keep oral medicine by mouth.
- You can likely complete at least 28 days of treatment, and your general activity level is 0–2 on the study scale (ECOG).
- Your AML must match the study type: relapsed or treatment-resistant AML with FLT3 being “wild type” (FLT3 WT).
- Your test results must show you have the needed mutation information, and you must have enough heart/kidney/liver function (kidney clearance and liver blood tests must be within allowed ranges).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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