Fetal airway balloon procedure for severe left lung underdevelopment
Part of Genetic & congenital clinical trials.
This pilot study tests a fetal procedure (placing a tiny balloon in the fetus’s airway) to improve lung growth in pregnancies affected by severe left congenital diaphragmatic hernia (CDH). You may be eligible if your baby’s condition is isolated to the left side and the testing shows very high lung underdevelopment, and if you can meet study and payment requirements.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be pregnant, age 18 or older, with a single (one) baby
- Your baby must have isolated left CDH (not right-sided or both sides), with the liver up
- Genetic testing must not show a harmful chromosome condition (normal karyotype confirmed by lab testing)
- Your pregnancy must be enrolled before 29 weeks 6 days, and the balloon procedure must happen between 27 weeks and 29 weeks 6 days
- Ultrasound must show severe lung underdevelopment (LHR O/E under 25%) at the time of surgery
- You must meet the study’s psychosocial support requirements and be able to get insurance approval or self-pay (or try Medicaid)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies a fetal procedure called FETO that places a small balloon in the baby’s windpipe to help the lungs grow in severe congenital diaphragmatic hernia (CDH). It may help babies with very small lung development after birth, but you must meet specific pregnancy, genetic, and safety requirements.
This study looks at placing a small balloon in a baby’s windpipe before birth to help severe congenital diaphragmatic hernia (CDH). The goal is to improve lung growth and birth outcomes by testing whether this timing and method can help babies with the most severe cases.
This trial studies whether placing a small balloon in the fetus’s airway during pregnancy (a procedure called FETO) can improve lung development and outcomes for babies with severe left congenital diaphragmatic hernia. You may be considered if the condition is isolated, very severe, and you can meet specific timing and follow-up requirements.
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