Clinical trials
Congenital Diaphragmatic Hernia clinical trials
Below are recruiting congenital diaphragmatic hernia clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07564297Enrolling by invitation
Long-term outcomes after fetal lung surgery for diaphragmatic hernia
This study follows babies born after a special fetal surgery (FETO) that places a temporary balloon in the baby's windpipe to help the lungs grow when they have a diaphragmatic hernia—a hole in the muscle that separates the chest from the belly. Researchers want to understand how these children do over time after this procedure.
Rochester, MinnesotaAges 18–50 - NCT04114578Recruiting
Study of babies and children with diaphragm hernia
This is an observational study that follows babies and children with congenital diaphragm hernia (CDH) to learn more about their health and care over time. It may help doctors better understand which factors affect outcomes.
Montreal, QuebecAges Up to 17 years - NCT04583644Recruiting
Fetal airway balloon procedure for severe left lung underdevelopment
This pilot study tests a fetal procedure (placing a tiny balloon in the fetus’s airway) to improve lung growth in pregnancies affected by severe left congenital diaphragmatic hernia (CDH). You may be eligible if your baby’s condition is isolated to the left side and the testing shows very high lung underdevelopment, and if you can meet study and payment requirements.
San Francisco, CaliforniaAges 18 years+ - NCT04774848Recruiting
Compare two breathing machines for newborns with diaphragmatic hernia
This study compares two types of ventilator support for newborns with congenital diaphragmatic hernia. The goal is to see which breathing approach works better and is safer when started very early after birth.
Salt Lake City, UtahAges Up to 1 day - NCT05100693Recruiting
FETO balloon removal during pregnancy for diaphragm hernia
This trial studies “smart removal” of a balloon placed in the womb to treat a baby’s congenital diaphragmatic hernia (CDH). It aims to see if removing the balloon in a planned, safer way can improve outcomes for the baby and keep mothers safe.
LeuvenAges 18 years+ - NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05213676RecruitingPhase 4
Testing stopping inhaled nitric oxide in newborns with CDH
This trial studies whether stopping inhaled nitric oxide (a breathing medicine) can be safely used in newborns with congenital diaphragmatic hernia (CDH). It may help the team decide the best way to use this medicine during early newborn care.
Birmingham, AlabamaAges birth–1 month - NCT05450653Recruiting
FETO balloon treatment for severe birth diaphragm hernia
This trial tests a special pregnancy procedure called FETO to help babies born with severe congenital diaphragm hernia (CDH) breathe better after birth. It may help by improving lung growth, but it requires close follow-up at a Chicago fetal center.
Chicago, IllinoisAges 18 years+ - NCT05461222Recruiting
Balloon treatment before birth for severe diaphragmatic hernia
This study looks at placing a small balloon in a baby’s windpipe before birth to help severe congenital diaphragmatic hernia (CDH). The goal is to improve lung growth and birth outcomes by testing whether this timing and method can help babies with the most severe cases.
Stanford, CaliforniaAges 18–50 - NCT05666986Recruiting
Sports and activity check-in for teens after diaphragmatic hernia surgery
This study looks at how adolescents who had diaphragmatic hernia surgery as babies engage in physical activities and sports. It will use questionnaires and an optional interview by video call to learn what helps or gets in the way—so care teams can better support families.
LilleAges 12–18 - NCT06408376Recruiting
Gentle cord clamping for babies with diaphragmatic hernia
This study compares a gentle way of clamping the umbilical cord after birth in babies with a diaphragmatic hernia. The goal is to see if this approach improves the baby's oxygen levels and reduces the need for breathing support.
Buenos AiresAges Any age - NCT06739356Recruiting
Balloon treatment study for severe diaphragmatic hernia in babies
This study tests a fetal surgery (fetoscopic tracheal balloon placement) to help lungs grow in babies with a severe hole in the diaphragm. It focuses on pregnancies where the liver is also in the chest and lung size is very small.
Houston, TexasAges 18 years+ - NCT07166172Recruiting
Long-term outcomes after fetal surgery for severe CDH
This study follows pregnant women and their babies after a special fetal surgery (FETO) for severe diaphragmatic hernia (CDH). It aims to understand long-term health outcomes for both mother and child.
Baltimore, MarylandAges 18 years+ - NCT00950118Recruiting
Study for people with congenital diaphragmatic hernia or family history
This study is for people who have a congenital diaphragmatic hernia (a birth-related opening in the diaphragm) or whose family member has had one. The research aims to learn more about the condition using molecular (cell-level) science, which may help improve understanding and future care.
Chicago, IllinoisAges Any age - NCT02986087Recruiting
FETO balloon procedure for severe congenital diaphragmatic hernia
This trial studies a fetal procedure called FETO (placing a small balloon in the baby’s windpipe) to help severe congenital diaphragmatic hernia babies develop better lungs before birth. It may help some babies whose scans suggest very limited lung growth, but it requires specific timing and pregnancy conditions.
Cincinnati, OhioAges 18–50 - NCT03138863Recruiting
FETO surgery to help a baby’s lungs in left diaphragmatic hernia
This trial studies a specialized pregnancy procedure (FETO) done to help babies with a defect in the diaphragm called congenital diaphragmatic hernia (CDH) grow better lungs before birth. It may help by improving lung development, based on how severe the baby’s lung underdevelopment looks on ultrasound, and it requires close follow-up at the study hospital.
Miami, FloridaAges 18–50 - NCT05354505Recruiting
Balloon procedure in pregnancy for severe diaphragmatic hernia
This trial studies a prenatal procedure called FETO, where a small balloon is placed in the fetal windpipe to help lung growth in babies with a severe diaphragmatic hernia. It may improve newborn outcomes by preparing the lungs before birth.
New York, New YorkAges 18 years+ - NCT07577414Recruiting
Fetal Treatment for Congenital Diaphragmatic Hernia
This trial tests a procedure called FETO (fetoscopic endoluminal tracheal occlusion) performed during pregnancy to help babies with congenital diaphragmatic hernia—a birth defect where part of the diaphragm (breathing muscle) has a hole and organs from the belly move into the chest. The procedure temporarily blocks the baby's windpipe to help the lungs grow bigger before birth.
Ann Arbor, MichiganAges 18 years+ - NCT05962346Recruiting
Pregnancy balloon procedure for severe left diaphragmatic hernia
This trial studies whether placing a small balloon in the fetus’s airway during pregnancy (a procedure called FETO) can improve lung development and outcomes for babies with severe left congenital diaphragmatic hernia. You may be considered if the condition is isolated, very severe, and you can meet specific timing and follow-up requirements.
Rochester, MinnesotaAges 18–50 - NCT05051254Recruiting
Breathing muscle testing in children with breathing muscle weakness
This study looks at how hard it is for children to breathe and how their breathing muscles work, using specific breathing-related tests. It may help doctors better understand breathing problems and choose care more effectively.
ParisAges birth–17 years - NCT06731855Recruiting
Recovery study: blood markers in newborns after intestine surgery
This study looks at blood markers in newborns after major stomach or intestine surgery. It aims to understand recovery and could help improve care for babies with similar conditions.
Liverpool, MerseysideAges Up to 5 days - NCT03750266Recruiting
3D models to help manage babies with diaphragmatic hernia
This study uses 3D animation and physical models to help plan care for pregnancies where the baby has diaphragmatic hernia (CDH). It may help patients and clinicians understand the baby’s condition better and make management decisions more easily.
Sheffield, South YorkshireAges 18 years+ - NCT05771688Recruiting
Balloon procedure for severe left lung birth defect
This trial studies a fetal procedure where doctors place a small balloon to help a severe left-sided lung birth defect (CDH) develop better. It aims to improve baby outcomes by temporarily blocking the airway in the womb, starting in a specific week range of pregnancy.
Minneapolis, MinnesotaAges 18 years+ - NCT06884423Recruiting
Balloon treatment for severe diaphragmatic hernia in unborn babies
This trial tests if placing a temporary balloon in the baby's windpipe before birth can improve survival for babies with a severe form of a diaphragmatic hernia. It is for pregnant women carrying a single baby with a left-sided hernia that is more severe or a right-sided hernia, and whose liver is up in the chest.
Philadelphia, PennsylvaniaAges 18 years+
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Congenital Diaphragmatic Hernia trials by city
Studies with a site in or near these metro areas.
Congenital Diaphragmatic Hernia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for congenital diaphragmatic hernia?
- Yes. Clin2 currently lists 32 recruiting congenital diaphragmatic hernia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital diaphragmatic hernia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital diaphragmatic hernia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.