Cross-linking donor tissue for keratoconus transplant
Part of Eyes & vision clinical trials.
This study tests whether treating donor corneal tissue with a special light and vitamin drops (called cross-linking) before a transplant helps improve outcomes for people with keratoconus. If you need a corneal transplant, this could strengthen the donor tissue and potentially reduce the need for future procedures.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 50 years old.
- You have keratoconus (a condition where the cornea thins and bulges) and need a corneal transplant.
- You have not had a corneal transplant or certain other corneal procedures (like cross-linking, intacs, or laser vision correction) before.
- You are willing to avoid additional corneal procedures during the study.
- If you are a woman who could become pregnant, you are not pregnant or nursing and use reliable birth control.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a same-day procedure that strengthens the cornea (the clear front part of the eye) in both eyes using a special light treatment, called cross-linking. It may help slow or stop the progression of keratoconus, a condition where the cornea becomes cone-shaped and causes blurry vision.
This study tests a procedure called corneal crosslinking to slow or stop the progression of keratoconus or corneal ectasia. It might help keep your cornea stable and prevent further vision loss.
This trial uses donated corneal tissue that was treated with a special light and riboflavin (collagen cross-linking) to strengthen it before transplant. The goal is to improve vision in people with severe keratoconus, a condition where the cornea bulges into a cone shape and gets very thin.
This trial studies collagen cross-linking, a procedure meant to strengthen a weakened cornea in people with keratoconus. It may help slow the bulging/weakening of the cornea and improve vision, and the study also uses special imaging to check changes over time.
This trial tests a new combined treatment for keratoconus that includes both a surface laser (phototherapeutic keratectomy) and corneal collagen crosslinking (CXL). It may help strengthen your cornea and improve vision.
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
Hear when a new Keratoconus trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.