Testing how opioid signals affect pain and social rejection
Part of Pain clinical trials.
This early-phase study looks at whether opioid system signals change how people feel pain and respond to feeling socially rejected, like after a breakup. It may help researchers understand why some people experience stronger pain or stress in response to rejection.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 55 years old
- Have not been diagnosed with a major mental health or brain condition
- Have not used drugs or had substance abuse in the last 6 months, and be abstinent from alcohol and substances for 48 hours
- Have no current pain and no history of long-term pain syndromes or neurological disorders
- Have had a recent unwanted romantic breakup
- Be able to safely do an MRI scan (no metal in your body and you can tolerate enclosed spaces)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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