Pain relief after thumb joint surgery: ibuprofen and acetaminophen versus oxycodone
Part of Pain clinical trials.
This study compares two ways to manage pain after thumb joint removal surgery: one using over-the-counter pain relievers (ibuprofen and acetaminophen) and the other using a prescription opioid (oxycodone). The goal is to see if the non-opioid option works just as well with fewer side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are scheduled to have a trapeziectomy (a surgery to remove the joint at the base of your thumb) because of thumb arthritis.
- You can speak and understand English well enough to fill out study forms.
- You are not pregnant.
- You are not currently taking strong pain relievers called opioids (like oxycodone, hydrocodone, or morphine).
- You do not have any allergies to ibuprofen (like Advil), acetaminophen (like Tylenol), or oxycodone.
- You do not have liver or kidney disease, heart failure, a past stomach or intestinal bleed, or a history of complex regional pain syndrome.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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