Pancreatic cancer biopsy-guided chemo before surgery
Treatments studied
Part of Cancer, Digestive system, Hormones & metabolism clinical trials.
This trial uses a special gene test on fluid taken from an endoscopic ultrasound (EUS) biopsy to help choose chemotherapy before surgery for pancreas cancer. It aims to see if this approach improves outcomes by matching treatment to the tumor’s RNA pattern.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Doctors are concerned you may have pancreatic adenocarcinoma and you plan an EUS biopsy (FNA) or you can provide saved biopsy tissue for testing.
- You must be age 18 or older and able to sign consent (or have a legal representative).
- A biopsy must already confirm adenocarcinoma (pancreatic cancer).
- Your cancer must look “resectable” or “borderline resectable” on CT/MRI (or in some cases locally advanced type), with no major spread to distant organs.
- You need enough blood counts and organ function to safely receive chemotherapy.
- You cannot have had chemotherapy or radiation in the past 3 years, and you cannot have certain infections (HIV, hepatitis B, or hepatitis C).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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