Chemo plus immunotherapy after surgery for esophageal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study looks at adding immunotherapy to standard chemotherapy after surgery for certain esophageal or EG-junction cancers. It may help lower the chance the cancer comes back, for people whose cancer can be fully removed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have confirmed esophageal cancer or EG-junction cancer (Siewert I or II).
- Your cancer can be removed with surgery, and the goal is cure/complete removal (not palliative treatment).
- Your heart and lungs are healthy enough to handle surgery.
- Your cancer has not spread to distant organs (not M1 stage).
- You are not being excluded due to an incomplete surgery (not R2 resection).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 3 trial tests whether adding immunotherapy to chemotherapy before surgery works better than chemotherapy alone for resectable esophageal cancer. The goal is to improve outcomes after tumor shrinkage before the operation.
This study tests a combination of chemotherapy and immunotherapy before and after standard chemoradiation for people with locally advanced esophageal squamous cell carcinoma. It aims to see if this approach can improve outcomes with manageable side effects.
This trial tests a treatment plan that combines chemotherapy with immunotherapy, followed by surgery, for people whose esophageal or stomach cancer has spread to a few areas (oligometastatic). The goal is to see if this approach can shrink the cancer and improve outcomes.
This trial tests whether adding immunotherapy to standard chemoradiation (chemotherapy plus radiation) can help preserve the esophagus and avoid surgery in people with resectable esophageal cancer. It aims to see if this combination is safer and more effective than current treatment.
This trial tests a treatment plan that combines chemotherapy and immunotherapy before surgery, followed by radiation and immunotherapy after surgery for people with esophageal squamous cell cancer. It aims to see if this approach helps prevent the cancer from coming back.
This trial tests whether giving chemotherapy combined with immunotherapy before surgery works better than the standard chemoradiation for esophageal cancer that can be removed. It may help reduce tumor size and improve outcomes.
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