Baloxavir and oseltamivir for severe flu in immune-compromised people
Treatments studied
Part of Blood & lymphatic, Cancer, Infections, Lungs & breathing clinical trials.
This trial tests whether two flu medicines—baloxavir and oseltamivir—work better to treat influenza in people with weakened immune systems (like transplant or blood cancer patients). It may help reduce severe complications, especially when flu affects the lungs or is at high risk to do so.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’ve had a stem cell (hematopoietic) transplant or you have a blood cancer
- You have confirmed flu on a PCR test (a lab test from a swab confirming influenza)
- Your flu illness shows signs of lung involvement, or it’s high-risk in the upper nose/throat even without lung signs
- You can take medicines by mouth (no major trouble swallowing or absorbing oral meds)
- You’re not on certain other flu antivirals or herbal flu treatments that are not allowed
- You are not needing a breathing machine and you can consent to the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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