Beta-blocker study for heart muscle function in young babies
Treatments studied
Part of Genetic & congenital, Heart & circulation clinical trials.
This trial tests whether a beta-blocker called propranolol can improve how well heart muscle cells work in very young babies with certain congenital heart conditions. It mainly looks at safety and how the medicine affects the heart, which could help guide future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a baby younger than 60 days old at the time of consent
- Have tetralogy of Fallot with pulmonary stenosis or double outlet right ventricle (DORV) confirmed by ultrasound/echocardiogram
- Weigh more than 2 kg and be able to take feeds by mouth or tube (enteral feeds)
- Be at least 35 weeks born (not too early/very premature)
- Not have a specific heart rhythm/electrical condition called atrioventricular block with a prolonged PR interval on EKG
- Not be taking medicines that interact with propranolol, and avoid metal implants
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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