Imaging brain changes in cocaine use or health controls
Part of Brain & nervous system, Mental health clinical trials.
This study uses a brain scan to look at changes in brain connections in people with cocaine use disorder, and compares them with healthy volunteers. It may help researchers understand how cocaine affects the brain and what biological signs could be targeted in the future.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be age 21 to 60
- For cocaine use disorder: you meet DSM-5 criteria for cocaine use disorder and your urine test is positive for recent cocaine use
- For healthy control participants: your urine drug test must be negative
- If you are female and can get pregnant: you must have a negative pregnancy blood test
- You should not have another main drug addiction besides nicotine (like alcohol or opioid use)
- You must be able to safely have MRI (and not have medical reasons you can’t)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how cravings for cocaine change over time in people who have recently stopped using. Researchers will measure brain activity to understand this process better.
This study tests a combination of brain stimulation (rTMS) and talk therapy (CBT) to help people reduce cocaine use. It's for adults who want treatment and use cocaine at least once a week.
This study tests whether a non-invasive brain stimulation method called tDCS can help reduce cocaine use. You would receive several sessions of mild electrical current applied to your scalp, which may help control cravings and improve your ability to stay abstinent.
This early-phase study uses brain imaging to understand how cocaine use disorder affects brain function. It may help researchers learn more about brain pathways involved in craving and treatment targets.
This study uses a special PET scan to look at how brain cells make energy, which may be changed by cocaine. It might help researchers find better ways to treat cocaine use disorder.
This early-phase study uses a PET brain scan (a special imaging test) to see how the brain responds in people with cocaine use disorder. It aims to better understand brain activity and whether this scan approach could help research or future treatments.
Hear when a new Cocaine Use Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.