Clin2
NCT04722978Possibly a fitRecruiting

Chemo plus moxifloxacin for metastatic triple-negative breast cancer

Triple Negative Breast Cancer

Part of Cancer, Skin clinical trials.

This trial tests whether adding moxifloxacin (an antibiotic) to standard chemotherapy helps people with metastatic triple-negative breast cancer live longer or respond better. You may qualify if your cancer has the right lab markers and you haven’t had treatment for metastatic disease yet.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
228 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • Your performance status is ECOG 0 to 1 (you’re able to do most daily activities).
  • Your tumor is triple-negative: ER negative, PR negative, and HER2 negative based on lab testing.
  • You have not had treatment after first recurrence or for metastatic disease.
  • You have at least one measurable tumor spot on scans.
  • Your blood test shows neutrophil-to-lymphocyte ratio (NLR) is 2 or higher.
  • Your heart and organs are strong enough for treatment (including LVEF on ultrasound/echo at least 45%).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06202313Not yet recruiting· Phase 2
Immunotherapy plus chemotherapy for metastatic triple-negative breast cancer

This trial tests a new immunotherapy drug (cadonilimab) combined with a chemotherapy (eribulin) against chemotherapy alone for triple-negative breast cancer that has come back or spread. If you receive the combination, the goal is to see if it helps control the cancer better or for longer.

Shenyang, Liaoning
NCT04301739Not yet recruiting· Phase 3
Immunotherapy plus chemo for triple-negative breast cancer

This trial tests whether adding an immunotherapy drug (HLX10) to chemotherapy before surgery, and then continuing it after surgery, helps people with triple-negative breast cancer more than chemotherapy alone. It is a type of breast cancer that does not respond to hormone treatments or HER2-targeted treatments.

NCT06229067Not yet recruiting· Phase 2
Immunotherapy plus oral chemotherapy for advanced triple-negative breast cancer

This trial tests a combination of an immunotherapy drug (PD-L1 antibody) along with a low-dose oral chemotherapy ('metronomic') called VEX for people with advanced triple-negative breast cancer. The goal is to see if this combination is safe and effective in controlling the cancer.

NCT05076682Recruiting· Phase 2
Study for hard-to-treat triple-negative breast cancer that keeps growing

This Phase 2 trial tests a treatment plan for triple-negative breast cancer that has come back or kept progressing after prior immunotherapy (sometimes along with targeted therapy or chemotherapy). It may help by trying to make the cancer more controllable when it has become resistant to earlier treatment.

Shanghai
NCT04159142Recruiting· Phase 2
Testing two chemo combos for advanced triple-negative breast cancer

This Phase 2 trial compares two chemotherapy combinations to see which works better for advanced triple-negative breast cancer. You would be asked to join one treatment arm based on study assignment and be followed for response and side effects.

Shijiazhuang, Hebei
NCT06134375Recruiting· Phase 1/Phase 2
TM plus capecitabine for triple-negative breast cancer

This trial tests a drug called tetrathiomolybdate (TM) combined with capecitabine for people with triple-negative breast cancer who still have cancer cells after standard chemotherapy and surgery. The goal is to see if this combination can help prevent the cancer from coming back.

Indianapolis, Indiana

Hear when a new Triple Negative Breast Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.