Studying a blood pressure medicine for dementia with Lewy bodies
Part of Brain & nervous system, Mental health clinical trials.
This trial tests a medicine normally used for high blood pressure (terazosin) to see if it can improve thinking or slow down decline in people with dementia with Lewy bodies. It's an early-stage study, so the goal is also to check safety.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have a diagnosis of dementia with Lewy bodies using standard criteria.
- Your score on a memory test (MoCA) must be 18 or higher.
- You need to have been on a stable dose of dementia medicines (donepezil, rivastigmine, galantamine, or memantine) for at least 4 weeks.
- Your blood pressure must not drop too low when standing up.
- You cannot be taking certain blood pressure medicines like doxazosin or tamsulosin.
- You must be generally healthy, and any conditions like high blood pressure or depression must be well controlled for at least 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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