Clin2
NCT07796308Possibly a fitNot yet recruiting

Testing terazosin for early Alzheimer's disease

Alzheimer s Disease

Treatments studied

Part of Brain & nervous system, Mental health clinical trials.

This trial tests a medicine called terazosin (currently used for blood pressure or prostate problems) to see if it can improve brain energy use and slow the effects of Alzheimer's disease. It's for people with mild symptoms, and the study will measure whether the drug is safe and helpful.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
100 people
Ages
50 years to 80 years
Study type
Interventional

Who can take part

  • Age 50 to 80 years old
  • Diagnosis of early Alzheimer's disease or mild cognitive impairment (MCI) due to Alzheimer's
  • Confirmed by a biomarker test (PET scan, spinal fluid, or blood test)
  • If taking Alzheimer's medications (donepezil, memantine, etc.), the dose must be stable for at least 4 weeks
  • Willing and able to have MRI scans and follow study procedures

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04760860Not yet recruiting· Phase 1/Phase 2
Studying a blood pressure medicine for dementia with Lewy bodies

This trial tests a medicine normally used for high blood pressure (terazosin) to see if it can improve thinking or slow down decline in people with dementia with Lewy bodies. It's an early-stage study, so the goal is also to check safety.

Iowa City, Iowa
NCT07224269Recruiting· Early Phase 1
Terazosin for energy in ALS patients

This study tests whether a medication called terazosin can boost energy levels in people with ALS (Lou Gehrig's disease). The goal is to see if it helps slow down the disease by supporting cell energy.

Iowa City, Iowa
NCT06885567Not yet recruiting· Phase 2
Testing a new drug for early Alzheimer's disease

This study tests an investigational drug called BEY2153 for people with early Alzheimer's disease. It aims to see if the drug is safe and can help slow memory decline.

Seoul
NCT07058688Recruiting· Phase 2
Testing a new drug for Alzheimer's (NTRX-07)

This study tests an experimental drug for Alzheimer's called NTRX-07. It aims to see if it can slow memory decline for people with mild to moderate Alzheimer's.

Brno
NCT07172815Not yet recruiting· Phase 2
Tadalafil for early Alzheimer's and memory loss

This study tests whether a daily pill (tadalafil, a type of medicine usually used for blood pressure or erectile dysfunction) can help people with early Alzheimer's or mild memory problems. It aims to see if this drug can improve memory and slow down the disease, with the help of regular checkups and brain scans.

NCT05282550Recruiting· Phase 2
Trazodone trial to improve sleep in early Alzheimer’s

This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.

Baltimore, Maryland

Hear when a new Alzheimer s Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.