Atorvastatin to improve brain blood flow in mild memory decline
Treatments studied
Part of Mental health clinical trials.
This Phase 2 study tests whether the cholesterol medicine atorvastatin can improve how well blood vessels in the brain respond in people with mild cognitive impairment (MCI). It may help brain circulation and possibly slow thinking and memory problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have mild cognitive impairment (CDR score 0.5 or 1.0).
- Your memory and thinking test scores are more than about 1.5 “normal” levels below what’s expected for your age and education.
- You are not diagnosed with dementia (you have not progressed to dementia).
- You have not been taking a statin (like atorvastatin, simvastatin, rosuvastatin) for the last 6 months.
- You can safely have MRI scans (for example, you don’t have MRI-incompatible metal or devices).
- You do not have recent stroke or heart attack (within the past 6 months) and no current substance abuse or known HIV.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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