Chemo with radiation versus chemo alone for older brain tumor patients
Part of Cancer clinical trials.
This trial compares two standard treatments for newly diagnosed glioblastoma (a serious brain cancer) in older and frail patients: chemo plus radiation versus chemo alone. It may help determine which approach works best and is safest for people in your age and health group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have newly diagnosed glioblastoma in the brain, confirmed by pathology (biopsy or surgery).
- Your MGMT lab test must be positive (including intermediate/indeterminate results).
- You’re age 65 or older, and your brain-function score (KPS) is between 60 and 70.
- You must be able to use a steady or decreasing steroid dose for at least 14 days before starting.
- Recent labs must be safe enough for treatment (blood counts, kidney, liver, and bilirubin levels).
- You must sign the study consent, and use very reliable birth control during treatment and for 6 months after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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