Study of keynatinib for certain hard-to-treat lymphomas
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This Phase 1 trial tests keynatinib, a new medicine, in people with specific types of lymphoma that have returned or not responded to earlier treatment. It aims to find a safe dose and see whether it can shrink tumors in the brain or elsewhere in the body, depending on the group.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and can sign consent and follow the study plan
- Your cancer must match one of these types: PCNSL, CLL/SLL, or mantle cell lymphoma
- You must have measurable tumor spots on CT or MRI (size rules will be checked)
- You must be well enough to tolerate treatment (ECOG performance score 0–2) and expected survival of at least 4 months
- Your blood counts and organ tests (kidneys, liver, clotting) must meet study thresholds
- If you can become pregnant or father a child, you must use effective birth control during the study and after
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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