Esketamine to reduce inflammation in septic adults
Treatments studied
Part of Infections clinical trials.
This trial studies whether esketamine can improve the body’s overactive inflammation during sepsis. Participants are adult ICU patients who are sick enough to need breathing support and have higher severity scores.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 60 years old
- Your sepsis illness score (SOFA) must be 2 or higher
- You need a breathing machine (mechanical ventilation) for at least 24 hours
- You (or your legal representative) must give informed consent
- You should not have had an organ or bone marrow transplant
- You should not have certain autoimmune diseases, blood cancers, recent chemo/radiation, or stronger immune-suppressing medicines
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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