Esketamine to prevent thinking problems after surgery in older adults
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether esketamine (a type of pain reliever) given after surgery can help older patients recover their thinking and memory better. You would be 65–90 years old and having a surgery lasting at least 2 hours.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 65 and 90 years old
- You are having non-heart surgery expected to last 2 hours or longer under general anesthesia
- You need pain medication through an IV pump that you control after surgery (called PCIA)
- You can hear, see, and communicate clearly before surgery
- You do not have schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis
- You have not had a traumatic brain injury or brain surgery in the past
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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