Treatment
Esketamine hydrochloride clinical trials
We’re tracking 8 recruiting studies that include Esketamine hydrochloride, each written for real people, not researchers, below.
Recruiting studies
- NCT05973851RecruitingPhase 3
Six-week medicine boost for depression after first treatment failure
This study tests a more intensive antidepressant medicine approach for people whose first tried treatment didn’t work well enough. It compares the intensified treatment with usual care, aiming to improve depression symptoms and daily functioning.
InnsbruckAges 18–65 - NCT06467513RecruitingPhase 4
Esketamine for lung problems after heart valve surgery
This study tests whether a medicine called esketamine can help prevent lung problems after heart valve surgery. If you are having valve replacement or repair with a heart-lung machine, you may be able to join.
Zunyi, GuizhouAges 18–75 - NCT05603104RecruitingPhase 3
Medication intensification after first treatment failure in mood and psychosis
This Phase 3 study tests a stronger medication approach after your first current treatment hasn’t worked well enough. It targets people with schizophrenia, major depressive disorder, or bipolar depression who still have significant symptoms and life impact.
Ramat GanAges 18–70 - NCT04843982RecruitingPhase 4
Esketamine to reduce inflammation in septic adults
This trial studies whether esketamine can improve the body’s overactive inflammation during sepsis. Participants are adult ICU patients who are sick enough to need breathing support and have higher severity scores.
Wuhan, HubeiAges 18–80 - NCT06579937RecruitingPhase 4
Esketamine for behavior after tonsil surgery in children
This study tests whether a medicine called esketamine can help reduce negative behavior changes in children after tonsillectomy or adenoidectomy surgery. Esketamine is given during anesthesia to see if it helps children recover with fewer emotional or behavioral issues.
Fuzhou, FujianAges 3–7 - NCT07369102RecruitingPhase 4
Esketamine with or without talk therapy for tough depression
This trial tests if adding a type of talk therapy called integration therapy helps esketamine work better for people with depression that hasn't improved with other treatments. You'll receive esketamine, and some people also get guided sessions to reflect on their experiences.
San JuanAges 21–65 - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT06744361RecruitingPhase 2
Ketamine after cardiac arrest to protect the brain
This trial tests whether the sedative drug ketamine, given after a cardiac arrest, can help protect the brain. It's for people whose heart stopped outside the hospital due to a shockable rhythm and who needed a breathing tube placed by emergency responders.
CopenhagenAges 18 years+
What Esketamine hydrochloride is being studied for
Conditions with recruiting Esketamine hydrochloride studies.
Common questions
- Are there clinical trials studying Esketamine hydrochloride?
- Yes. Clin2 currently lists 8 recruiting studies that include Esketamine hydrochloride, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Esketamine hydrochloride trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Esketamine hydrochloride an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Esketamine hydrochloride or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.